Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NAAA | Q02083 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11276627 | 0.83 | ABCB11 (0.45) | ABCB11LMNAMAPTMAPK1ALDH1A1 | |
| SCHEMBL11292673 | 0.83 | MAPT (0.65) | ABCB11LMNAMAPTMAPK1ALDH1A1 | |
| SCHEMBL11272380 | 0.82 | LMNA (0.54) | ABCB11LMNAMAPTMAPK1ALDH1A1 | |
| SCHEMBL11261351 | 0.82 | POLB (0.38) | ABCB11LMNAMAPTMAPK1ALDH1A1 | |
| SCHEMBL11271674 | 0.82 | POLB (0.43) | LMNAMAPTMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11269559 | 0.81 | MAPT (0.43) | ABCB11LMNAMAPTMAPK1ALDH1A1 | |
| SCHEMBL11267481 | 0.80 | LMNA (0.44) | LMNANPC1RAB9A | |
| SCHEMBL11267391 | 0.80 | LMNA (0.61) | ABCB11LMNAMAPTMAPK1ALDH1A1 | |
| SCHEMBL11210936 | 0.79 | NAAA (0.40) | NAAAALDH1A1CYP4F2CYP4A11IGF1R | |
| SCHEMBL11270277 | 0.78 | LMNA (0.56) | ABCB11LMNAMAPTMAPK1NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4324796-A | HYPOGLYCEMIC AGENTS, HYPOKETONEMIC AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1982-04-13 | — | — | US | disclosed |