Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.36 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formamide SCHEMBL11440222 | 0.93 | TDP1 (0.44) | TDP1CYP1A2KDM4EMAPTAKR1B1 | |
| SCHEMBL11249938 | 0.89 | TDP1 (0.45) | TDP1CYP1A2KDM4EMAPTAKR1B1 | |
| SCHEMBL11250215 | 0.87 | TDP1 (0.46) | TDP1CYP1A2KDM4EMAPTAKR1B1 | |
| SCHEMBL11260792 | 0.86 | TDP1 (0.43) | TDP1CYP1A2KDM4EMAPTAKR1B1 | |
| SCHEMBL11255746 | 0.84 | ALDH1A1 (0.40) | KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL14755876 | 0.82 | KDM4E (0.59) | TDP1CYP1A2KDM4EMAPTAKR1B1 | |
| SCHEMBL11257657 | 0.82 | LMNA (0.46) | KDM4EMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11254420 | 0.82 | PKM (0.45) | TDP1KDM4EMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL11311256 | 0.81 | TDP1 (0.53) | TDP1CYP1A2KDM4EMAPTAKR1B1 | |
| SCHEMBL11251937 | 0.81 | TDP1 (0.46) | TDP1CYP1A2KDM4EMAPTAKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337256-A | ANTIINFLAMMATORY AGENTS; ANTIAGGLOMERANTS; ENZYME INHIBITORS; ANTIULCER AGENTS | TEIKOKU HORMONE MANUFACTURING CO., LTD. (JP) | 1982-06-29 | — | — | US | disclosed |
| US-4329288-A | CONTRAGESTATIONAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1982-05-11 | — | — | US | disclosed |
| EP-0013411-A1 | Isoquinoline derivatives, process for their preparation and pharmaceutical compositions containing them | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1980-07-23 | — | — | EP | disclosed |