Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | TNKS | O95271 | 2/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 8/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 8/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2461750 | 0.87 | XDH (0.48) | XDHTNKSPARP1GABRA1GABRB2 | |
| SCHEMBL11660795 | 0.82 | DHFR (0.46) | XDHTNKSPARP1GABRA1GABRB2 | |
| SCHEMBL9319191 | 0.82 | TNKS (0.56) | XDHTNKSPARP1GABRA1GABRB2 | |
| SCHEMBL9285299 | 0.80 | XDH (0.42) | XDHTNKSPARP1GABRA1GABRB2 | |
| SCHEMBL27771899 | 0.78 | SHBG (0.48) | XDHTNKSPARP1GABRA1GABRB2 | |
| SCHEMBL18657227 | 0.78 | GABRA1 (0.52) | XDHTNKSPARP1GABRA1GABRB2 | |
| SCHEMBL9285307 | 0.78 | XDH (0.41) | XDHTNKSPARP1GABRA1GABRB2 | |
| SCHEMBL9703377 | 0.78 | XDH (0.41) | XDHTNKSPARP1GABRA1GABRB2 | |
| SCHEMBL822357 | 0.77 | TNKS (0.40) | XDHTNKSPARP1GABRA1GABRB2 | |
| SCHEMBL9453990 | 0.77 | TNKS (0.41) | XDHTNKSPARP1GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4319052-A | Method for preparing sterically hindered bis- or polyphenols | STYSKIN EVGENY L | 1982-03-09 | — | — | US | claimed |
| US-4319052-A | Method for preparing sterically hindered bis- or polyphenols | STYSKIN EVGENY L | 1982-03-09 | — | — | US | disclosed |
| US-4319052-A | Method for preparing sterically hindered bis- or polyphenols | STYSKIN EVGENY L | 1982-03-09 | — | — | US | disclosed |