SCHEMBL11261642

SCHEMBL11261642

CCOC(=O)C(C)(C)Oc1c(C)cc2c(c1C)c(-c1ccncc1)c1n2CCCCC1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.38
GAA P10253 3/20 0.38
ALOX15 P16050 1/20 0.38
ACHE P22303 3/20 0.36
MAPK1 P28482 2/20 0.34
TRPM2 O94759 1/20 0.33
CNR1 P21554 1/20 0.32
CNR2 P34972 1/20 0.32
CYP1A2 P05177 2/20 0.32
CYP3A4 P08684 2/20 0.32
KMT2A Q03164 2/20 0.32
MEN1 O00255 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
ABCB11 O95342 1/20 0.31
TSHR P16473 1/20 0.31
HTR2A P28223 1/20 0.31
PMP22 Q01453 1/20 0.31
PPARA Q07869 1/20 0.31
THRB P10828 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11271278 0.89 PPARA (0.36) CYP1A2CYP3A4KMT2AMEN1CYP2C9
SCHEMBL11255435 0.81 GAA (0.46) ALDH1A1GAAALOX15MAPK1CNR1
SCHEMBL11264489 0.81 GAA (0.42) ALDH1A1GAAALOX15ACHEMAPK1
SCHEMBL11267432 0.80 GAA (0.45) ALDH1A1GAAALOX15MAPK1CNR1
SCHEMBL11267995 0.76 ADORA3 (0.40) ALDH1A1GAAALOX15ACHECYP1A2
SCHEMBL11266222 0.72 GAA (0.48) ALDH1A1GAAALOX15MAPK1CYP1A2
SCHEMBL11259633 0.69 GAA (0.44) ALDH1A1GAAALOX15MAPK1CYP1A2
SCHEMBL11261802 0.69 TBXAS1 (0.38) ALDH1A1GAAALOX15CYP1A2CYP3A4
SCHEMBL11260420 0.69 GAA (0.39) ALDH1A1GAAALOX15MAPK1CNR1
SCHEMBL11269896 0.68 GAA (0.38) ALDH1A1GAAALOX15MAPK1CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4343811-A ATHEROSCLEROSIS BOEHRINGER INGELHEIM GMBH (DE) 1982-08-10 US disclosed