Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 16/20 | 0.36 |
| ▸ | PPARG | P37231 | 14/20 | 0.36 |
| ▸ | PPARD | Q03181 | 12/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11261642 | 0.89 | ALDH1A1 (0.38) | PPARACYP1A2CYP2C9MEN1CYP3A4 | |
| SCHEMBL11260420 | 0.79 | GAA (0.39) | PPARAPPARGPPARDCYP1A2CYP2C9 | |
| SCHEMBL11261802 | 0.79 | TBXAS1 (0.38) | PPARAPPARGPPARDCYP1A2CYP2C9 | |
| SCHEMBL11267995 | 0.79 | ADORA3 (0.40) | CYP1A2CYP2C9MEN1CYP3A4CYP2C19 | |
| SCHEMBL11269896 | 0.78 | GAA (0.38) | PPARAPPARGPPARDCYP1A2CYP2C9 | |
| SCHEMBL11269891 | 0.70 | HTR6 (0.38) | CYP1A2CYP2C9MEN1CYP3A4CYP2C19 | |
| SCHEMBL11264489 | 0.70 | GAA (0.42) | PPARAPPARGCYP1A2CYP3A4KMT2A | |
| SCHEMBL11255435 | 0.70 | GAA (0.46) | PPARAPPARGCYP1A2CYP3A4 | |
| SCHEMBL11267432 | 0.69 | GAA (0.45) | PPARAPPARGCYP1A2CYP3A4 | |
| SCHEMBL11262244 | 0.64 | GAA (0.42) | CYP1A2CYP2C9MEN1CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0015523-B1 | INDOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE FOR MEDICAMENTS | Dr. Karl Thomae GmbH (DE) | 1982-10-13 | — | — | EP | disclosed |