Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | PTPRB | P23467 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MLYCD | O95822 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | RXRG | P48443 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11266609 | 0.88 | MLYCD (0.40) | ALDH1A1HPGDPTPRBHSD17B10AGBL2 | |
| SCHEMBL11271862 | 0.85 | ALDH1A1 (0.36) | ALDH1A1HPGDPTPRBHSD17B10AGBL2 | |
| SCHEMBL11263310 | 0.84 | L3MBTL1 (0.49) | ALDH1A1L3MBTL1RAB9AMLYCDPOLB | |
| SCHEMBL11266630 | 0.79 | ALDH1A1 (0.38) | ALDH1A1HPGDPTPRBHSD17B10AGBL2 | |
| SCHEMBL11275694 | 0.75 | STK17A (0.33) | ALDH1A1HPGDHSD17B10POLB | |
| Hydrochloric Acid SCHEMBL14988832 | 0.75 | LMNA (0.52) | ALDH1A1HPGDPTPRBHSD17B10GRIN2D | |
| SCHEMBL3708106 | 0.75 | LMNA (0.52) | ALDH1A1HPGDPTPRBHSD17B10GRIN2D | |
| SCHEMBL11345743 | 0.74 | GRN (0.33) | ALDH1A1RAB9APOLBSMN1; SMN2EGLN1 | |
| SCHEMBL11268219 | 0.74 | NR1H3 (0.38) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL11261894 | 0.74 | PGR (0.38) | HSD17B10TSHRMLYCDLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4322434-A | N-Substituted-4-(polyfluoro-2-hydroxy-2-propyl)anilines and compounds related thereto | SCHERING CORPORATION (US) | 1982-03-30 | — | — | US | disclosed |
| US-4267193-A | N-substituted-4-(polyfluoro-2-hydroxy-2-propyl)anilines and compounds related thereto | SCHERING CORPORATION (US) | 1981-05-12 | — | — | US | disclosed |