Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 6/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 6/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 10/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 10/20 | 0.48 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11281283 | 0.86 | LMNA (0.53) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL11258032 | 0.84 | HDAC3 (0.52) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL11255256 | 0.82 | HDAC3 (0.52) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL11253350 | 0.80 | ADRB2 (0.56) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL11257434 | 0.77 | ATP4A (0.53) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL11252882 | 0.77 | ATP4A (0.53) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL11248636 | 0.76 | ADRB2 (0.57) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL11244652 | 0.74 | CYP2D6 (0.58) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL11257221 | 0.72 | — | — | |
| SCHEMBL27202465 | 0.72 | NPC1 (0.71) | S1PR1NPC1POLBRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4338330-A | HYPOTENSIVE AGENTS | CONTINENTAL PHARMA (BE) | 1982-07-06 | — | — | US | disclosed |