Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 10/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 10/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 10/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 10/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 10/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 10/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 10/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 10/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 10/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 10/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 10/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.48 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | MMP13 | P45452 | 2/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11258032 | 0.85 | HDAC3 (0.52) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL11253350 | 0.83 | ADRB2 (0.56) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL11262467 | 0.82 | HDAC3 (0.48) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL11572413 | 0.81 | ADRB1 (0.60) | ADRB1ADRB3 | |
| SCHEMBL11257434 | 0.79 | ATP4A (0.53) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL11252882 | 0.79 | ATP4A (0.53) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL11281283 | 0.78 | LMNA (0.53) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL11170530 | 0.76 | ADRB1 (0.66) | ADRB1ADRB3LMNANFKB1 | |
| SCHEMBL11248636 | 0.76 | ADRB2 (0.57) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL11572635 | 0.76 | ADRB3 (0.61) | ADRB1ADRB3NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4338330-A | HYPOTENSIVE AGENTS | CONTINENTAL PHARMA (BE) | 1982-07-06 | — | — | US | disclosed |