Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | FBP1 | P09467 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11252988 | 0.79 | PARP1 (0.40) | TDP1SMN1; SMN2POLBMAPT | |
| SCHEMBL11262689 | 0.76 | TDP1 (0.44) | ALDH1A1TDP1SMN1; SMN2CYP1A2POLB | |
| SCHEMBL5657561 | 0.73 | TDP1 (0.49) | ALDH1A1FBP1TDP1SMN1; SMN2POLB | |
| SCHEMBL27648083 | 0.73 | ALDH1A1 (0.57) | ALDH1A1TDP1APEX1SMN1; SMN2MAPK1 | |
| SCHEMBL4270672 | 0.69 | TDP1 (0.60) | ALDH1A1FBP1TDP1CYP1A2TSHR | |
| SCHEMBL8172704 | 0.69 | FBP1 (0.49) | ALDH1A1FBP1TDP1SMN1; SMN2CYP1A2 | |
| SCHEMBL3535123 | 0.68 | GPR35 (0.54) | ALDH1A1FBP1TDP1APEX1CYP1A2 | |
| SCHEMBL9608361 | 0.68 | ALDH1A1 (0.47) | ALDH1A1FBP1TDP1APEX1CYP1A2 | |
| SCHEMBL17224000 | 0.66 | TDP1 (0.42) | ALDH1A1FBP1TDP1APEX1CYP1A2 | |
| Alcohol SCHEMBL27961237 | 0.66 | ALDH1A1 (0.79) | ALDH1A1TDP1MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4363909-A | ANTIVIRAL AGENTS | RHONE POULENC INDUSTRIES (FR) | 1982-12-14 | — | — | US | disclosed |