Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.60 |
| ▸ | NPC1 | O15118 | 5/20 | 0.60 |
| ▸ | RAB9A | P51151 | 5/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | KDR | P35968 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | PLEC | Q15149 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8299753 | 0.87 | TDP1 (0.68) | SMN1; SMN2NPC1RAB9ALMNAKMT2A | |
| SCHEMBL9867402 | 0.86 | KDR (0.70) | SMN1; SMN2NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL5503426 | 0.84 | NPC1 (0.58) | SMN1; SMN2NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL9868437 | 0.84 | KDM4E (0.59) | SMN1; SMN2NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL30117873 | 0.83 | RAB9A (0.79) | SMN1; SMN2NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL3096372 | 0.83 | RAB9A (0.79) | SMN1; SMN2NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL10352137 | 0.82 | METAP2 (0.60) | SMN1; SMN2NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL8341671 | 0.82 | POLB (0.63) | SMN1; SMN2NPC1RAB9ALMNAKMT2A | |
| SCHEMBL12949077 | 0.81 | NPC1 (0.56) | SMN1; SMN2NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL3088776 | 0.80 | NPC1 (0.55) | SMN1; SMN2NPC1RAB9ALMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4261730-A | ALTER MALE REPRODUCTIVE COMPONENTS OF CORN PLANT | MONSANTO COMPANY (US) | 1981-04-14 | — | — | US | claimed |
| US-4347075-A | Method for using nicotinic acid derivatives as plant growth regulants | MONSANTO COMPANY (US) | 1982-08-31 | — | — | US | disclosed |
| US-4261730-A | ALTER MALE REPRODUCTIVE COMPONENTS OF CORN PLANT | MONSANTO COMPANY (US) | 1981-04-14 | — | — | US | disclosed |
| US-4086078-A | LEGUMINOUS PLANTS | MONSANTO COMPANY (US) | 1978-04-25 | — | — | US | disclosed |