Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3102422 | 0.89 | RAB9A (0.56) | KDM4ERAB9ANPC1TDP1SMN1; SMN2 | |
| SCHEMBL8299753 | 0.86 | TDP1 (0.68) | KDM4ERAB9ANPC1TDP1SMN1; SMN2 | |
| SCHEMBL9867402 | 0.85 | KDR (0.70) | RAB9ANPC1GRM4TDP1SMN1; SMN2 | |
| SCHEMBL11264182 | 0.84 | SMN1; SMN2 (0.60) | KDM4ERAB9ANPC1TDP1SMN1; SMN2 | |
| SCHEMBL5503426 | 0.82 | NPC1 (0.58) | KDM4ERAB9ANPC1TDP1SMN1; SMN2 | |
| SCHEMBL3088776 | 0.82 | NPC1 (0.55) | KDM4ERAB9ANPC1GRM4TDP1 | |
| SCHEMBL10352137 | 0.81 | METAP2 (0.60) | KDM4ERAB9ANPC1TDP1SMN1; SMN2 | |
| SCHEMBL8341671 | 0.81 | POLB (0.63) | KDM4ERAB9ANPC1TDP1SMN1; SMN2 | |
| SCHEMBL12949077 | 0.80 | NPC1 (0.56) | KDM4ERAB9ANPC1TDP1SMN1; SMN2 | |
| SCHEMBL28199290 | 0.80 | KDM4E (0.73) | KDM4ERAB9ATDP1SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5077408-A | PROCESS FOR THE SYNTHESIS OF OXAZOLOPYRIDINE COMPOUNDS | SCIENCE ET ORGANISATION (FR) | 1991-12-31 | — | — | US | disclosed |
| US-5061713-A | NO ANTIINFLAMMATORY ACTIVITY | SCIENCE ET ORGANIZATION (FR) | 1991-10-29 | — | — | US | disclosed |