SCHEMBL1126419

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1127594	0.95	MAPT (0.37)	SLC2A1POLBMAPTLMNAMEN1
	SCHEMBL1127913	0.93	MAPT (0.42)	SLC2A1MAPTMAPK1SMN1; SMN2FYN
	SCHEMBL1126552	0.92	MAPT (0.39)	SLC2A1POLBMAPTLMNAMEN1
	SCHEMBL1998014	0.91	MEN1 (0.40)	SLC2A1POLBMAPTLMNAMEN1
	SCHEMBL1126434	0.91	MAPT (0.39)	SLC2A1POLBMAPTLMNAMEN1
	SCHEMBL1126954	0.90	MAPT (0.38)	SLC2A1POLBMAPTLMNAMEN1
	SCHEMBL1126732	0.90	MAPT (0.38)	SLC2A1POLBMAPTLMNAMEN1
	SCHEMBL1988343	0.90	DRD2 (0.38)	MAPTLMNAMEN1KMT2ATSHR
	SCHEMBL1126741	0.89	LMNA (0.39)	SLC2A1POLBMAPTLMNAMEN1
	SCHEMBL1126825	0.89	LMNA (0.39)	SLC2A1POLBMAPTLMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.