SCHEMBL1127913

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1126419	0.93	SLC2A1 (0.40)	MAPTMAPK1SMN1; SMN2FYNSLC2A1
	SCHEMBL1127594	0.92	MAPT (0.37)	MAPTMAPK1SMN1; SMN2HTR1ADRD2
	SCHEMBL1126552	0.87	MAPT (0.39)	MAPTMAPK1SLC2A1HTT
	SCHEMBL1988343	0.87	DRD2 (0.38)	MAPTMAPK1SMN1; SMN2HTR1ADRD2
	SCHEMBL1998014	0.86	MEN1 (0.40)	MAPTMAPK1SLC2A1HTT
	SCHEMBL1126434	0.86	MAPT (0.39)	MAPTMAPK1SLC2A1
	SCHEMBL1126954	0.85	MAPT (0.38)	MAPTMAPK1SMN1; SMN2SLC2A1
	SCHEMBL1126732	0.85	MAPT (0.38)	MAPTMAPK1SLC2A1
	SCHEMBL1126741	0.85	LMNA (0.39)	MAPTMAPK1SLC2A1NAMPTNPY2R
	SCHEMBL1126825	0.84	LMNA (0.39)	MAPTMAPK1SLC2A1NPY2RHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.