Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | BCAT1 | P54687 | 2/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 3/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.33 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11269382 | 0.81 | HPGD (0.39) | ALDH1A1KMT2AMEN1TSHRHSD17B10 | |
| SCHEMBL11411696 | 0.77 | KDM4E (0.49) | ALDH1A1KMT2AMEN1POLBTSHR | |
| SCHEMBL11277795 | 0.75 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1POLBTSHR | |
| SCHEMBL10654484 | 0.70 | LMNA (0.41) | ALDH1A1KMT2AMEN1POLBTSHR | |
| SCHEMBL11277132 | 0.70 | ALDH1A1 (0.39) | ALDH1A1KMT2AMEN1POLBTSHR | |
| SCHEMBL11277143 | 0.70 | RECQL (0.53) | ALDH1A1KMT2AMEN1POLBTSHR | |
| SCHEMBL29334591 | 0.70 | USP14 (0.39) | ALDH1A1KMT2AMEN1POLBTSHR | |
| SCHEMBL21666684 | 0.70 | KDM4E (0.44) | ALDH1A1KMT2AMEN1POLBTSHR | |
| SCHEMBL15128455 | 0.69 | KDM4E (0.52) | ALDH1A1KMT2AMEN1POLBTSHR | |
| SCHEMBL17367052 | 0.69 | L3MBTL1 (0.57) | ALDH1A1KMT2AMEN1POLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4316904-A | Indolopyrone tetrazoles and carboxamidotetrazoles having antiallergic activity | WARNER-LAMBERT COMPANY | 1982-02-23 | — | — | US | disclosed |