Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.38 |
| ▸ | MYLK | Q15746 | 1/20 | 0.37 |
| ▸ | GPR3 | P46089 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11284898 | 0.84 | KDM4E (0.40) | HPGDKDM4EHSD17B10ALDH1A1MEN1 | |
| SCHEMBL11267749 | 0.83 | RAB9A (0.35) | HPGDKDM4EHSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL11273839 | 0.83 | CYP1A2 (0.45) | HPGDKDM4EHSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL11264400 | 0.81 | ALDH1A1 (0.44) | HPGDKDM4EHSD17B10ALDH1A1TSHR | |
| SCHEMBL11278189 | 0.75 | KDM4E (0.50) | HPGDEGFRKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL11269004 | 0.74 | EGFR (0.43) | HPGDEGFRSRCKDM4ENQO2 | |
| SCHEMBL7384714 | 0.70 | POLB (0.54) | HPGDEGFRKDM4ENQO2HSD17B10 | |
| SCHEMBL10918652 | 0.69 | PABPC1 (0.41) | HPGDEGFRSRCKDM4EHSD17B10 | |
| SCHEMBL11274440 | 0.69 | HSD17B10 (0.51) | HPGDKDM4EHSD17B10ALDH1A1TSHR | |
| SCHEMBL9636992 | 0.69 | PRKDC (0.49) | HPGDKDM4EHSD17B10ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4316904-A | Indolopyrone tetrazoles and carboxamidotetrazoles having antiallergic activity | WARNER-LAMBERT COMPANY | 1982-02-23 | — | — | US | disclosed |