SCHEMBL1127012

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1126471	0.89	LMNA (0.38)	NPC1RAB9ANPY2RALDH1A1LMNA
	SCHEMBL1126444	0.88	NPC1 (0.41)	NPC1RAB9ACHRM1CHRM5CHRM3
	SCHEMBL1993424	0.87	SLC2A1 (0.37)	NPC1RAB9ANPY2RSMN1; SMN2ALDH1A1
	SCHEMBL1128005	0.86	MAPT (0.36)	CHRM3NPY2RALDH1A1MEN1MAPT
	SCHEMBL1993703	0.85	LMNA (0.37)	NPC1RAB9ANPY2RSMN1; SMN2ALDH1A1
	SCHEMBL1127036	0.84	LMNA (0.37)	NPC1RAB9ANPY2RSMN1; SMN2ALDH1A1
	SCHEMBL1126811	0.83	MAPT (0.36)	CHRM3LMNAMAPT
	SCHEMBL1127558	0.82	ALDH1A1 (0.37)	NPC1RAB9ASMN1; SMN2ALDH1A1LMNA
	SCHEMBL1127916	0.82	MAPT (0.36)	NPC1RAB9ANPY2RALDH1A1LMNA
	SCHEMBL1126481	0.82	KCNA5 (0.41)	NPC1RAB9ASMN1; SMN2ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.