Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.71 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.71 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.69 |
| ▸ | ELANE | P08246 | 18/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11526487 | 0.85 | LMNA (0.71) | ALDH1A1LMNACYP3A4HIF1AADRB2 | |
| SCHEMBL23339689 | 0.85 | LMNA (0.71) | ALDH1A1LMNACYP3A4HIF1AADRB2 | |
| Dipivefrin SCHEMBL29710905 | 0.83 | HIF1A (1.00) | ALDH1A1LMNACYP3A4HIF1AADRB2 | |
| Dipivefrin SCHEMBL24714 | 0.83 | HIF1A (1.00) | ALDH1A1LMNACYP3A4HIF1AADRB2 | |
| Dipivefrin SCHEMBL24713 | 0.83 | HIF1A (1.00) | ALDH1A1LMNACYP3A4HIF1AADRB2 | |
| Dipivefrin SCHEMBL20673238 | 0.83 | HIF1A (1.00) | ALDH1A1LMNACYP3A4HIF1AADRB2 | |
| Dipivefrin SCHEMBL41351 | 0.82 | ADRB2 (1.00) | ALDH1A1LMNACYP3A4HIF1AADRB2 | |
| Dipivefrin SCHEMBL41350 | 0.82 | ADRB2 (1.00) | ALDH1A1LMNACYP3A4HIF1AADRB2 | |
| SCHEMBL11275258 | 0.82 | LMNA (0.78) | ALDH1A1LMNACYP3A4HIF1AADRB2 | |
| Dipivefrin SCHEMBL5275338 | 0.82 | ADRB2 (1.00) | ALDH1A1LMNACYP3A4HIF1AADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4338323-A | Piperidylbenzimidazolinone derivatives | SCIENCE UNION ET CIE (FR) | 1982-07-06 | — | — | US | disclosed |