Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CDC25B | P30305 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CDC25A | P30304 | 1/20 | 0.40 |
| ▸ | CDC25C | P30307 | 1/20 | 0.40 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.38 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7060201 | 0.83 | ALDH1A1 (0.46) | ALDH1A1HPGDCDC25BKDM4ECDC25A | |
| SCHEMBL11252362 | 0.82 | CASP1 (0.48) | ALDH1A1HPGDKMT2A | |
| SCHEMBL11381253 | 0.80 | ALDH1A1 (0.38) | ALDH1A1HPGDCDC25BCDC25ACDC25C | |
| SCHEMBL11265183 | 0.79 | EPHX2 (0.38) | ALDH1A1HPGDKDM4EKMT2A | |
| SCHEMBL846623 | 0.78 | ALDH1A1 (0.49) | ALDH1A1HPGDCDC25BKDM4ECDC25A | |
| SCHEMBL11266327 | 0.78 | MMP8 (0.47) | ALDH1A1KMT2A | |
| SCHEMBL11255136 | 0.78 | ALDH1A1 (0.51) | ALDH1A1KDM4EKMT2A | |
| SCHEMBL14582249 | 0.76 | ALDH1A1 (0.45) | ALDH1A1HPGDCDC25BKDM4ECDC25A | |
| SCHEMBL1433197 | 0.76 | ALDH1A1 (0.53) | ALDH1A1HPGDCDC25BKDM4ECDC25A | |
| SCHEMBL11580303 | 0.76 | ALDH1A1 (0.47) | ALDH1A1HPGDCDC25BCDC25ACDC25C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4360520-A | 1,4-Dihydropyridazine compounds, and their medicinal use | BAYER AKTIENGESELLSCHAFT (DE) | 1982-11-23 | — | — | US | disclosed |