Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | TERT | O14746 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPY4R | P50391 | 2/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11268000 | 0.91 | OPRM1 (0.37) | OPRM1OPRD1OPRK1TERTHTR2C | |
| SCHEMBL11256464 | 0.89 | POLB (0.40) | OPRM1OPRD1OPRK1TERTHTR2C | |
| SCHEMBL11272890 | 0.86 | OPRM1 (0.38) | OPRM1OPRD1OPRK1HTR2CALDH1A1 | |
| SCHEMBL11266562 | 0.84 | DRD2 (0.39) | OPRM1OPRD1OPRK1ALDH1A1POLB | |
| SCHEMBL11258040 | 0.83 | OPRM1 (0.37) | OPRM1OPRD1OPRK1HTR2CALDH1A1 | |
| SCHEMBL11269476 | 0.78 | KDM4E (0.40) | OPRM1OPRD1OPRK1ALDH1A1POLB | |
| SCHEMBL11265320 | 0.76 | HTR2C (0.41) | OPRM1OPRD1OPRK1HTR2CALDH1A1 | |
| SCHEMBL11262480 | 0.75 | HTR2C (0.40) | OPRM1OPRD1OPRK1HTR2CALDH1A1 | |
| Hydrochloric Acid SCHEMBL11254022 | 0.74 | RAD52 (0.41) | OPRM1OPRD1OPRK1HTR2CALDH1A1 | |
| SCHEMBL11256981 | 0.72 | SMN1; SMN2 (0.41) | OPRM1OPRD1OPRK1HTR2CALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344946-A | ANTIARTHRITICS, ANTIRHEUMATICS | BOEHRINGER INGELHEIM GMBH (DE) | 1982-08-17 | — | — | US | disclosed |