Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11258040 | 0.81 | OPRM1 (0.37) | KDM4EALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL11265320 | 0.74 | HTR2C (0.41) | ALDH1A1TSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11269478 | 0.73 | EGFR (0.47) | KDM4EALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL11256981 | 0.70 | SMN1; SMN2 (0.41) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11260549 | 0.69 | HTR2C (0.36) | TSHRMEN1KMT2AMAPK1POLB | |
| SCHEMBL11254903 | 0.67 | NPC1 (0.43) | ALDH1A1TSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL27494737 | 0.66 | TSHR (0.51) | KDM4EALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL27479846 | 0.65 | MAPT (0.48) | KDM4EALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL11255635 | 0.64 | HTR2C (0.41) | ALDH1A1MEN1KMT2AOPRM1OPRD1 | |
| SCHEMBL11270188 | 0.63 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2AOPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344946-A | ANTIARTHRITICS, ANTIRHEUMATICS | BOEHRINGER INGELHEIM GMBH (DE) | 1982-08-17 | — | — | US | disclosed |