Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 9/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11256464 | 0.94 | POLB (0.40) | POLBOPRM1OPRD1OPRK1ALDH1A1 | |
| SCHEMBL11268000 | 0.86 | OPRM1 (0.37) | POLBOPRM1OPRD1OPRK1LMNA | |
| SCHEMBL11265290 | 0.84 | AKR1C3 (0.36) | POLBOPRM1OPRD1OPRK1ALDH1A1 | |
| SCHEMBL11272890 | 0.83 | OPRM1 (0.38) | POLBOPRM1OPRD1OPRK1ALDH1A1 | |
| SCHEMBL11258040 | 0.80 | OPRM1 (0.37) | OPRM1OPRD1OPRK1ALDH1A1CYP1A2 | |
| SCHEMBL11256220 | 0.77 | EPHX2 (0.41) | DRD2KCNH2OPRM1OPRD1OPRK1 | |
| SCHEMBL11269476 | 0.77 | KDM4E (0.40) | POLBOPRM1OPRD1OPRK1ALDH1A1 | |
| SCHEMBL11257677 | 0.76 | DRD2 (0.40) | DRD2KCNH2OPRM1OPRD1OPRK1 | |
| Water SCHEMBL11255617 | 0.75 | DRD2 (0.39) | DRD2KCNH2OPRM1OPRD1OPRK1 | |
| SCHEMBL11266555 | 0.74 | ALDH1A1 (0.48) | POLBALDH1A1LMNANPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344946-A | ANTIARTHRITICS, ANTIRHEUMATICS | BOEHRINGER INGELHEIM GMBH (DE) | 1982-08-17 | — | — | US | disclosed |