SCHEMBL1126557

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1992813	0.86	MAPT (0.39)	LMNAUSP2MAPTGAAHSD17B10
	SCHEMBL1126854	0.86	GFER (0.39)	USP2MAPTGAAALDH1A1KDM4E
	SCHEMBL1127022	0.86	MAPT (0.42)	LMNAUSP2MAPTGAAHSD17B10
	SCHEMBL1126589	0.85	LMNA (0.39)	LMNAUSP2MAPTGAAHSD17B10
	SCHEMBL1127165	0.82	MALT1 (0.41)	LMNAUSP2MAPTGAAALDH1A1
	SCHEMBL1126825	0.82	LMNA (0.39)	LMNAUSP2MAPTGAAHSD17B10
	SCHEMBL1126488	0.80	MAPT (0.37)	LMNAUSP2MAPTGAATSHR
	SCHEMBL1987403	0.79	ALDH1A1 (0.40)	LMNAUSP2MAPTGAAHSD17B10
	SCHEMBL1126563	0.77	LMNA (0.39)	LMNAUSP2MAPTGAAHSD17B10
	SCHEMBL1126441	0.77	TSHR (0.38)	USP2MAPTGAAALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.