Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1989883 | 0.83 | LMNA (0.56) | NPSR1LMNASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL18878423 | 0.82 | NPSR1 (0.49) | NPSR1LMNASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL8203695 | 0.77 | NPSR1 (0.51) | NPSR1LMNASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL3575608 | 0.73 | ALDH1A1 (0.42) | NPSR1LMNAALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL3585516 | 0.73 | LDHA (0.33) | LMNAALDH1A1KMT2AMEN1POLB | |
| SCHEMBL7293758 | 0.72 | LMNA (0.56) | NPSR1LMNASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL5596728 | 0.71 | NPSR1 (0.38) | NPSR1LMNASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL18891701 | 0.71 | RAB9A (0.43) | NPSR1LMNASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL7256405 | 0.71 | NPSR1 (0.79) | NPSR1LMNASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL10717916 | 0.69 | LMNA (0.56) | NPSR1LMNASMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283006-B1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2015-02-25 | — | — | EP | disclosed |
| EP-2626361-B1 | Pyrrole antifungal agents | F2G LTD (GB) | 2014-10-15 | — | — | EP | disclosed |
| EP-2626361-A1 | Pyrrole antifungal agents | F2G Limited (GB) | 2013-08-14 | — | — | EP | disclosed |
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | disclosed |