Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KDR | P35968 | 6/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1127545 | 0.81 | RAB9A (0.50) | RAB9ANPC1SMN1; SMN2POLBMAPT | |
| SCHEMBL1126693 | 0.74 | MEN1 (0.49) | SMN1; SMN2POLBMAPTKDM4ELMNA | |
| SCHEMBL1127158 | 0.73 | FAAH (0.42) | RAB9ANPC1SMN1; SMN2POLBMAPT | |
| SCHEMBL23880568 | 0.73 | KDR (0.70) | RAB9ANPC1SMN1; SMN2POLBMAPT | |
| SCHEMBL651159 | 0.72 | KDR (0.74) | RAB9ANPC1SMN1; SMN2POLBMAPT | |
| SCHEMBL1126845 | 0.72 | HCRTR1 (0.41) | RAB9ANPC1SMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL1127139 | 0.71 | MAPT (0.48) | RAB9ANPC1SMN1; SMN2POLBMAPT | |
| SCHEMBL1126561 | 0.71 | MAPT (0.41) | RAB9ANPC1POLBMAPTKDM4E | |
| SCHEMBL8115181 | 0.70 | TRPV1 (0.65) | RAB9ANPC1SMN1; SMN2POLBMAPT | |
| SCHEMBL13134245 | 0.69 | KDM4E (0.63) | RAB9ANPC1SMN1; SMN2POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | disclosed |