Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | LTA4H | P09960 | 3/20 | 0.37 |
| ▸ | PORCN | Q9H237 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | FLT1 | P17948 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1127228 | 0.81 | FAAH (0.40) | FAAHEPHX2HDAC4BRD4LTA4H | |
| SCHEMBL1127168 | 0.76 | CHRNA7 (0.39) | NPC1RAB9ASMN1; SMN2MEN1TP53 | |
| SCHEMBL1127139 | 0.76 | MAPT (0.48) | NPC1RAB9ASMN1; SMN2PKMMEN1 | |
| SCHEMBL1127213 | 0.74 | NPC1 (0.39) | FAAHEPHX2HDAC4LTA4HPORCN | |
| SCHEMBL1126595 | 0.73 | RAB9A (0.48) | HDAC4NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL1645643 | 0.73 | L3MBTL1 (0.53) | FAAHEPHX2HDAC4LTA4HNPC1 | |
| SCHEMBL1126845 | 0.72 | HCRTR1 (0.41) | PORCNNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL28723922 | 0.72 | HDAC4 (0.50) | FAAHEPHX2HDAC4LTA4HNPC1 | |
| SCHEMBL1126693 | 0.71 | MEN1 (0.49) | SMN1; SMN2NFKB1MEN1KMT2APOLB | |
| SCHEMBL1126737 | 0.70 | BRD4 (0.38) | BRD4SMN1; SMN2KMT2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | disclosed |