SCHEMBL1127545

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1126931	0.83	RAB9A (0.46)	RAB9ANPC1SMN1; SMN2POLBMAPT
	SCHEMBL1126595	0.81	RAB9A (0.48)	RAB9ANPC1KDRSMN1; SMN2POLB
	SCHEMBL1126812	0.79	ALDH1A1 (0.48)	RAB9ANPC1SMN1; SMN2POLBKDM4E
	SCHEMBL1127110	0.77	L3MBTL1 (0.46)	RAB9AMAPTKDM4ETRPV1
	SCHEMBL1126896	0.75	RAB9A (0.49)	RAB9ANPC1KDRSMN1; SMN2POLB
	SCHEMBL1127303	0.75	CHRNB2 (0.50)	RAB9ANPC1SMN1; SMN2MAPTKDM4E
	SCHEMBL1127233	0.74	MEN1 (0.50)	SMN1; SMN2MAPTKDM4ELMNAHDAC6
	SCHEMBL23880568	0.74	KDR (0.70)	RAB9ANPC1KDRSMN1; SMN2POLB
	SCHEMBL651159	0.74	KDR (0.74)	RAB9ANPC1KDRSMN1; SMN2POLB
	SCHEMBL1127228	0.74	FAAH (0.40)	RAB9ANPC1SMN1; SMN2POLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.