Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 2/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP12 | P39900 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CPA1 | P15085 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27719934 | 0.93 | RAB9A (0.56) | MDM2MMP2MMP9MMP12RAB9A | |
| SCHEMBL4257686 | 0.88 | MDM2 (0.66) | MDM2MMP2MMP9MMP12ALDH1A1 | |
| SCHEMBL20766143 | 0.80 | CPA1 (0.51) | PPARGPPARAALDH1A1KMT2ACPA1 | |
| SCHEMBL8335791 | 0.80 | CPA1 (0.51) | PPARGPPARAALDH1A1KMT2ACPA1 | |
| SCHEMBL1303759 | 0.80 | ALDH1A1 (0.50) | ALDH1A1LMNAKMT2A | |
| SCHEMBL31561615 | 0.80 | MDM2 (0.51) | MDM2MMP2MMP9MMP12RAB9A | |
| SCHEMBL1304165 | 0.79 | NPC1 (0.53) | RAB9AALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL1302717 | 0.78 | CES2 (0.53) | MDM2RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL19953141 | 0.75 | EPHX1 (0.44) | PPARGPPARACPA1PTPN1 | |
| SCHEMBL10656178 | 0.74 | MDM2 (0.47) | MDM2RAB9AALDH1A1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101250133-B | Novel method for synthesizing (+/-)p-fluoro-2-(2-methyl-propionyl)-4-oxygen-N,3-diphenyl-benzenebutanamide and intermediate therein | INST MATERIA MEDICA CAMS | 2010-06-09 | — | — | CN | claimed |
| CN-101250133-A | Novel method for synthesizing (+/-)p-fluoro-2-(2-methyl-propionyl)-4-oxygen-N,3-diphenyl-benzenebutanamide and intermediate therein | INST MATERIA MEDICA CAMS (CN) | 2008-08-27 | — | — | CN | claimed |
| CN-100368386-C | Method for synthesizing (+/-) p-fluoro-2- (2-methyl-propionyl) -4-oxy-N, 3-diphenyl-phenylbutylamide and intermediate thereof | INST OF MEDICAL MATERIALS CHIN (CN) | 2008-02-13 | — | — | CN | claimed |
| CN-1325844-A | Novel synthesis method of (+/-) p-fluoro-2- (2-methyl-propionyl) -4-oxo-N, 3-diphenyl-phenylbutylamide and intermediate thereof | INST OF MEDICAL MATERIALS CHIN (CN) | 2001-12-12 | — | — | CN | claimed |
| CN-101250133-B | Novel method for synthesizing (+/-)p-fluoro-2-(2-methyl-propionyl)-4-oxygen-N,3-diphenyl-benzenebutanamide and intermediate therein | INST MATERIA MEDICA CAMS | 2010-06-09 | — | — | CN | disclosed |
| CN-101250133-A | Novel method for synthesizing (+/-)p-fluoro-2-(2-methyl-propionyl)-4-oxygen-N,3-diphenyl-benzenebutanamide and intermediate therein | INST MATERIA MEDICA CAMS (CN) | 2008-08-27 | — | — | CN | disclosed |
| CN-100368386-C | Method for synthesizing (+/-) p-fluoro-2- (2-methyl-propionyl) -4-oxy-N, 3-diphenyl-phenylbutylamide and intermediate thereof | INST OF MEDICAL MATERIALS CHIN (CN) | 2008-02-13 | — | — | CN | disclosed |
| CN-1325844-A | Novel synthesis method of (+/-) p-fluoro-2- (2-methyl-propionyl) -4-oxo-N, 3-diphenyl-phenylbutylamide and intermediate thereof | INST OF MEDICAL MATERIALS CHIN (CN) | 2001-12-12 | — | — | CN | disclosed |
| US-4349557-A | ANTIDEPRESSANTS | SYNTHELABO (FR) | 1982-09-14 | — | — | US | disclosed |