Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.37 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.37 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.37 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.37 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.37 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1448749 | 0.82 | PTGS1 (0.53) | PKMCYP1A2PDE10APTGDRKDM4E | |
| SCHEMBL6944394 | 0.81 | KDM4E (0.47) | PIK3CDPIK3CAPIK3CBPIK3CGCYP1A2 | |
| SCHEMBL11276685 | 0.81 | TTR (0.46) | CYP1A2PDE10ATUBB4ATUBBTUBA3C | |
| SCHEMBL11271678 | 0.81 | CYP11B1 (0.42) | CYP1A2PDE10ATUBB4ATUBBTUBA3C | |
| SCHEMBL11272789 | 0.80 | CYP1A2 (0.51) | PIK3CDPIK3CAPIK3CBPIK3CGPKM | |
| SCHEMBL11273634 | 0.79 | CYP1A2 (0.50) | PKMCYP1A2PDE10APTGDRKDM4E | |
| SCHEMBL11471488 | 0.76 | PTGS1 (0.68) | KDM4ETDP1ALDH1A1HSD17B10NPC1 | |
| SCHEMBL77974 | 0.74 | CA2 (0.61) | PIK3CDPIK3CAPIK3CBPIK3CGCYP1A2 | |
| SCHEMBL6561661 | 0.73 | KDM4E (0.59) | CYP1A2KDM4ETDP1NPC1L3MBTL1 | |
| SCHEMBL12900679 | 0.72 | ALDH1A1 (0.40) | CYP1A2KDM4EALDH1A1CYP3A4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4327022-A | Heterocyclic alkyl naphthols | STERLING DRUG INC. (US) | 1982-04-27 | — | — | US | disclosed |
| US-4169108-A | 5(OR 6)-[(Substituted-amino)alkyl]-2,3-naphthalenediols | STERLING DRUG INC. (US) | 1979-09-25 | — | — | US | disclosed |