Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NQO1 | P15559 | 1/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11266053 | 0.81 | PIK3CD (0.40) | KDM4ETDP1RAB9ANPC1THRB | |
| SCHEMBL25629899 | 0.80 | CYP1A2 (0.50) | KDM4ERAB9ANPC1ACHEALDH1A1 | |
| SCHEMBL15345390 | 0.79 | DHODH (0.46) | KDM4ERAB9AACHEALDH1A1HPGD | |
| SCHEMBL10391434 | 0.77 | KDM4E (0.53) | KDM4ETDP1NPC1TNFMAPT | |
| SCHEMBL11272789 | 0.77 | CYP1A2 (0.51) | KDM4ETDP1RAB9ANPC1THRB | |
| SCHEMBL6100006 | 0.76 | ACHE (0.57) | KDM4EACHEALDH1A1HPGDHSD17B10 | |
| SCHEMBL77974 | 0.74 | CA2 (0.61) | KDM4EALDH1A1HSD17B10PIK3CDPIK3CA | |
| SCHEMBL11471351 | 0.74 | ALDH1A1 (0.56) | KDM4ETDP1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL31074286 | 0.74 | ALDH1A1 (0.56) | KDM4ETDP1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL11466634 | 0.73 | ALDH1A1 (0.49) | KDM4ERAB9ANPC1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003104167-A2 | CYANOHYDRIN ETHERS AND ESTERS AS HIGH-SENSITIVITY ENZYME SUBSTRATES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2003-12-18 | — | — | WO | disclosed |
| US-20030207344-A1 | Cyanohydrin ethers and esters as high-sensitivity enzyme substrates | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2003-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030207344-A1 | Cyanohydrin ethers and esters as high-sensitivity enzyme substrates | HPD, BCKDK, PCK1 | KDM4E 669/4885TDP1 2827/4885RAB9A 4819/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.