Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | STAT1 | P42224 | 1/20 | 0.44 |
| ▸ | BRAF | P15056 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11254846 | 0.85 | EPHX2 (0.46) | GAAEPHX2RAB9ATRPV1NPC1 | |
| SCHEMBL11261749 | 0.84 | RAB9A (0.46) | GAAEPHX2SMN1; SMN2RAB9ATRPV1 | |
| SCHEMBL11264322 | 0.81 | GAA (0.52) | GAAKDM4EEPHX2RAB9ATRPV1 | |
| SCHEMBL11253471 | 0.79 | NPC1 (0.52) | GAAEPHX2SMN1; SMN2RAB9ATRPV1 | |
| SCHEMBL11295953 | 0.77 | EPHX2 (0.49) | EPHX2SMN1; SMN2RAB9ATRPV1NPC1 | |
| SCHEMBL11268396 | 0.77 | GAA (0.50) | GAACYP1A2CYP2C19EPHX2SMN1; SMN2 | |
| SCHEMBL11296385 | 0.76 | IL2 (0.51) | CYP1A2EPHX2SMN1; SMN2RAB9ATRPV1 | |
| SCHEMBL11271217 | 0.75 | LMNA (0.46) | GAAKDM4ESMN1; SMN2RAB9ANPC1 | |
| SCHEMBL11300373 | 0.75 | RAB9A (0.56) | EPHX2SMN1; SMN2RAB9ATRPV1NPC1 | |
| SCHEMBL10869152 | 0.73 | KDM4E (0.58) | GAAATMBRAFKDM4EEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336264-A | 1-Benzoyl-3-(isoxazolyl or benzisoxazolyl)-ureas and insecticidal use thereof | ELI LILLY AND COMPANY (US) | 1982-06-22 | — | — | US | claimed |