Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 7/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.35 |
| ▸ | WNT3A | P56704 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.34 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11266558 | 0.80 | MTNR1A (0.38) | MTNR1ANPC1RAB9AHPGDALDH1A1 | |
| SCHEMBL11201763 | 0.72 | MTNR1A (0.45) | TACR1MTNR1ANPC1RAB9AHPGD | |
| SCHEMBL11204329 | 0.70 | ADRB2 (0.46) | MTNR1AALDH1A1 | |
| SCHEMBL3648434 | 0.67 | CTNNB1 (0.47) | MTNR1ANPC1RAB9AHPGDALDH1A1 | |
| SCHEMBL11196742 | 0.67 | HPGD (0.54) | NPC1RAB9AHPGDALDH1A1POLB | |
| SCHEMBL11655675 | 0.67 | HPGD (0.57) | NPC1RAB9AHPGDALDH1A1PSMB8 | |
| SCHEMBL7526194 | 0.66 | MTNR1A (0.68) | MTNR1ARAB9AHPGDALDH1A1 | |
| SCHEMBL11201767 | 0.66 | MTNR1A (0.42) | MTNR1ANPC1RAB9AHPGDSHMT2 | |
| SCHEMBL6188980 | 0.66 | HPGD (0.53) | NPC1RAB9AHPGDALDH1A1POLB | |
| SCHEMBL7518458 | 0.66 | MTNR1A (0.69) | MTNR1ANPC1RAB9AHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4327113-A | DRUGS FOR TREATMENT OF HEART DISEASES, ADRENERGIC BLOCKING AGENTS, ETC | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1982-04-27 | — | — | US | disclosed |