Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | GRN | P28799 | 1/20 | 0.43 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11264480 | 0.75 | KMT2A (0.60) | ALDH1A1HPGDALOX15KDM4ESMN1; SMN2 | |
| SCHEMBL13928594 | 0.74 | ALDH1A1 (0.62) | ALDH1A1HPGDALOX15HSD17B10KDM4E | |
| SCHEMBL11266631 | 0.73 | SMN1; SMN2 (0.41) | ALDH1A1HPGDHSD17B10SMN1; SMN2RAB9A | |
| SCHEMBL11266339 | 0.72 | KDM4E (0.41) | ALDH1A1KDM4E | |
| SCHEMBL4642665 | 0.71 | ALDH1A1 (0.69) | ALDH1A1HPGDALOX15HSD17B10KDM4E | |
| SCHEMBL11267948 | 0.71 | MAPT (0.51) | ALDH1A1HPGDKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL11266822 | 0.68 | ALOX15 (0.53) | ALDH1A1ALOX15HSD17B10SMN1; SMN2NPC1 | |
| SCHEMBL11267199 | 0.68 | SMN1; SMN2 (0.44) | ALDH1A1HPGDALOX15KDM4ESMN1; SMN2 | |
| SCHEMBL27347353 | 0.68 | ALDH1A1 (0.74) | ALDH1A1HPGDALOX15HSD17B10KDM4E | |
| SCHEMBL12647223 | 0.67 | ALDH1A1 (0.62) | ALDH1A1HPGDALOX15HSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329363-A | Substituted mercapto acid amides and their use | MERCK & CO., INC. (US) | 1982-05-11 | — | — | US | disclosed |
| US-4216160-A | IMMUNOREGULANTS FOR CORRECTING AN INBALANCE OF IMMUNE HOMEOSTASIS | MERCK & CO., INC. (US) | 1980-08-05 | — | — | US | disclosed |