SCHEMBL1126724

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21751965	0.79	NOTUM (0.54)	NOTUMALDH1A1KMT2AGABRA1GABRB2
	SCHEMBL891107	0.78	GABRA1 (0.42)	ALDH1A1GABRA1GABRB2AKR1C2PTGS1
	SCHEMBL1126625	0.77	ALDH1A1 (0.49)	ALDH1A1KMT2ALMNACYP2C9TSHR
	SCHEMBL969678	0.73	NOTUM (0.48)	NOTUMALDH1A1KMT2AGABRA1GABRB2
	SCHEMBL157592	0.72	FOLH1 (0.53)	ALDH1A1KMT2AGABRA1GABRB2LMNA
	SCHEMBL5842251	0.71	NOTUM (0.45)	NOTUMALDH1A1KMT2A
	SCHEMBL17799517	0.71	FOLH1 (0.52)	ALDH1A1KMT2AGABRA1GABRB2LMNA
	SCHEMBL70047	0.69	NOTUM (0.65)	NOTUMALDH1A1KMT2ATSHRHPGD
	SCHEMBL27418750	0.69	ADRB3 (0.39)	ALDH1A1GABRA1GABRB2AKR1C2AKR1C1
	SCHEMBL1356439	0.69	ACE2 (0.50)	ALDH1A1SGK1CAMKK2ADRB3TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.