Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 7/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11267446 | 0.80 | TDP1 (0.42) | CNR1CNR2TDP1L3MBTL1IDO1 | |
| SCHEMBL13506110 | 0.79 | GAA (0.48) | LMNAALDH1A1ESR1CYP3A4ESR2 | |
| SCHEMBL7561836 | 0.79 | GAA (0.48) | LMNAALDH1A1ESR1CYP3A4ESR2 | |
| SCHEMBL7721313 | 0.79 | GAA (0.48) | LMNAALDH1A1ESR1CYP3A4ESR2 | |
| SCHEMBL7948711 | 0.75 | HTR1B (0.49) | TDP1L3MBTL1LMNAALDH1A1ESR1 | |
| SCHEMBL11209066 | 0.73 | ESR1 (0.54) | LMNAALDH1A1ESR1CYP3A4MAPT | |
| SCHEMBL9661912 | 0.72 | ESR1 (0.47) | LMNAALDH1A1ESR1CYP3A4MAPT | |
| SCHEMBL8768148 | 0.69 | TDP1 (0.50) | TDP1L3MBTL1LMNAHSD17B10ALDH1A1 | |
| SCHEMBL9451160 | 0.69 | CA2 (0.53) | CNR1CNR2LMNAHSD17B10ESR1 | |
| SCHEMBL16807278 | 0.68 | L3MBTL1 (0.80) | CNR1CNR2TDP1L3MBTL1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3240771-B1 | PROCESS FOR THE PREPARATION OF OSPEMIFENE AND FISPEMIFENE | OLON SPA (IT) | 2019-02-20 | — | — | EP | disclosed |
| US-9975832-B2 | Process for the preparation of ospemifene and fispemifene | OLON S.P.A. (IT) | 2018-05-22 | — | — | US | disclosed |
| US-20170342007-A1 | PROCESS FOR THE PREPARATION OF OSPEMIFENE AND FISPEMIFENE | OLON S.P.A. (IT) | 2017-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170342007-A1 | PROCESS FOR THE PREPARATION OF OSPEMIFENE AND FISPEMIFENE | CYP2F1, FOXO1, NFE2L2 | CNR1 4124/4885CNR2 3534/4885TDP1 4312/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.