SCHEMBL1126754

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1126614	0.92	NPC1 (0.48)	NPY2RMTTPNPC1RAB9AMAPT
	SCHEMBL1127172	0.87	NPY2R (0.45)	NPY2RMTTPSMN1; SMN2NPC1RAB9A
	SCHEMBL1989043	0.85	MAPT (0.38)	MAPTTP53KDM4EPOLB
	SCHEMBL1990333	0.79	MAPKAPK2 (0.41)	NPY2RNPC1RAB9AMAPTCYP3A4
	SCHEMBL1127012	0.78	NPC1 (0.40)	NPY2RSMN1; SMN2NPC1RAB9AMAPT
	SCHEMBL1999344	0.77	MAPT (0.41)	RAB9AMAPTMEN1KMT2AALDH1A1
	SCHEMBL1126788	0.76	KDM4E (0.46)	NPY2RMTTPSMN1; SMN2NPC1RAB9A
	SCHEMBL1993424	0.76	SLC2A1 (0.37)	NPY2RSMN1; SMN2NPC1RAB9AMAPT
	SCHEMBL23488090	0.76	WDR5 (0.33)	NPY2RSMN1; SMN2NPC1RAB9AMAPT
	SCHEMBL24584695	0.76	WDR5 (0.33)	NPY2RSMN1; SMN2NPC1RAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.