SCHEMBL1126768

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1126872	0.76	CA12 (0.41)	—
	SCHEMBL12605596	0.75	ALDH1A1 (0.40)	TAAR1MAPTCYP2C19
	SCHEMBL30478876	0.72	ITGB2 (0.39)	HTR2AKDM1AHTR2CTAAR1HTR6
	SCHEMBL1126326	0.72	HTR6 (0.37)	HTR2AKDM1AHTR2CHTR6HTR7
	SCHEMBL28210243	0.70	AR (0.40)	TSHR
	SCHEMBL1127117	0.70	KDM4E (0.39)	MAPTLMNASLC2A1
	SCHEMBL28196405	0.69	CYP11B1 (0.53)	MAPTCYP1A2CYP2D6CYP2C19SIGMAR1
	SCHEMBL1126850	0.69	SLC18A3 (0.45)	MAPTCYP1A2CYP2D6CYP2C19
	SCHEMBL1126509	0.69	HTR2A (0.42)	HTR2AHTR2CLSSTAAR1HTR6
	SCHEMBL7656510	0.68	TAAR1 (0.42)	TAAR1KDM5AKDM5BTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.