SCHEMBL1126926

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1126990	0.80	CNR1 (0.45)	ALDH1A1CNR1BRD4SMN1; SMN2KDM4E
	SCHEMBL1126844	0.78	KDM4E (0.46)	ALDH1A1CNR1BRD4SMN1; SMN2NPC1
	SCHEMBL1127015	0.78	RAB9A (0.49)	ALDH1A1NPC1RAB9ARECQLTSHR
	SCHEMBL1126684	0.77	KDM4E (0.50)	KDM4E
	SCHEMBL1126694	0.77	BRD4 (0.42)	ALDH1A1BRD4KDM4E
	SCHEMBL1126839	0.77	ALDH1A1 (0.46)	ALDH1A1BRD4SMN1; SMN2KDM4ERECQL
	SCHEMBL1127040	0.77	ALDH1A1 (0.38)	ALDH1A1CNR1BRD4SMN1; SMN2NPC1
	SCHEMBL1127357	0.77	BRD4 (0.37)	ALDH1A1CNR1BRD4SMN1; SMN2NPC1
	SCHEMBL1126957	0.77	ALDH1A1 (0.50)	ALDH1A1SMN1; SMN2CYP1A2CYP2C9CYP2C19
	SCHEMBL1126929	0.75	TYR (0.46)	ALDH1A1BRD4KDM4EADORA2BTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.