Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KISS1R | Q969F8 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 2/20 | 0.35 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.34 |
| ▸ | CTSK | P43235 | 2/20 | 0.34 |
| ▸ | CAPN9 | O14815 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CTSH | P09668 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSC | P53634 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11236002 | 0.91 | CYP1A2 (0.33) | KISS1RMMP8CPB2MMECYP3A4 | |
| SCHEMBL11209304 | 0.86 | MMP8 (0.39) | KISS1RMMP8CPB2MMECAPN1 | |
| SCHEMBL11207356 | 0.84 | NPY4R (0.46) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL11352509 | 0.84 | NPY4R (0.47) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL9069166 | 0.83 | NPY4R (0.43) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL11210981 | 0.82 | ADRA1A (0.45) | KISS1RMMP8CPB2MMEMAPK1 | |
| SCHEMBL10919519 | 0.82 | NPY4R (0.44) | NPY4RNPY1RNPY2RNPY5RFCER2 | |
| SCHEMBL9068526 | 0.81 | NPY4R (0.40) | CPB2MMENPY4RNPY1RNPY2R | |
| SCHEMBL18379446 | 0.81 | USP2 (0.47) | KISS1RMMP8TSHRUSP2NPY4R | |
| SCHEMBL11208669 | 0.81 | ADRA1A (0.47) | KISS1RMMP8CPB2MMEMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4327111-A | N-Substituted mercaptoacyl pripionamides | E. R. SQUIBB & SONS, INC. (US) | 1982-04-27 | — | — | US | claimed |
| US-4327111-A | N-Substituted mercaptoacyl pripionamides | E. R. SQUIBB & SONS, INC. (US) | 1982-04-27 | — | — | US | disclosed |