Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MDM4 | O15151 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11282166 | 0.85 | KMT2A (0.54) | KMT2AMEN1LMNATSHR | |
| SCHEMBL280229 | 0.81 | MMP8 (0.56) | MMP8PIN1KMT2AMEN1NPC1 | |
| SCHEMBL340846 | 0.81 | MMP8 (0.56) | MMP8PIN1KMT2AMEN1NPC1 | |
| SCHEMBL8129701 | 0.81 | MMP8 (0.56) | MMP8PIN1KMT2AMEN1NPC1 | |
| Hydrochloric Acid SCHEMBL1630960 | 0.79 | PIN1 (0.54) | MMP8PIN1KMT2AMEN1NPC1 | |
| Hydrochloric Acid SCHEMBL1851016 | 0.79 | PIN1 (0.54) | MMP8PIN1KMT2AMEN1NPC1 | |
| Hydrochloric Acid SCHEMBL28989563 | 0.79 | PIN1 (0.54) | MMP8PIN1KMT2AMEN1NPC1 | |
| SCHEMBL11274448 | 0.78 | PIN1 (0.33) | MMP8PIN1KMT2AMEN1NPC1 | |
| SCHEMBL27342597 | 0.76 | MMP8 (0.48) | MMP8PIN1KMT2AMEN1NPC1 | |
| SCHEMBL1516027 | 0.74 | MMP8 (0.53) | MMP8PIN1KMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344956-A | Oxotetrahydrothiophenes | ERCOLI NICOLO | 1982-08-17 | — | — | US | disclosed |