Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | METAP2 | P50579 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11269036 | 0.78 | MMP8 (0.46) | PIN1MEN1KMT2ANPC1TSHR | |
| SCHEMBL11286439 | 0.71 | ALDH1A1 (0.49) | KMT2ANPC1POLBRAB9AHSD17B10 | |
| SCHEMBL11274455 | 0.68 | CYP2D6 (0.31) | PIN1L3MBTL1METAP2 | |
| SCHEMBL10275655 | 0.67 | ALDH1A1 (0.46) | PIN1MEN1KMT2ANPC1HSD17B10 | |
| SCHEMBL6936995 | 0.67 | ESR1 (0.47) | NPC1RAB9AMMP8ALDH1A1KDM4E | |
| SCHEMBL11387979 | 0.66 | NAPRT (0.39) | MEN1KMT2ATSHRHSD17B10KDM4E | |
| SCHEMBL28379607 | 0.66 | GRIN2D (0.33) | RAB9ATSHRKDM4ECYP1A2 | |
| SCHEMBL2262877 | 0.64 | KMT2A (0.38) | PIN1MEN1KMT2ANPC1POLB | |
| SCHEMBL2262880 | 0.64 | KMT2A (0.38) | PIN1MEN1KMT2ANPC1POLB | |
| SCHEMBL11282166 | 0.63 | KMT2A (0.54) | MEN1KMT2ATSHRHSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344956-A | Oxotetrahydrothiophenes | ERCOLI NICOLO | 1982-08-17 | — | — | US | disclosed |