Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.72 |
| ▸ | MPO | P05164 | 3/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | APEX1 | P27695 | 1/20 | 0.62 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.61 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11116603 | 0.86 | KMT2A (0.69) | POLBMPOKMT2ASMN1; SMN2HPGD | |
| SCHEMBL8797365 | 0.84 | KMT2A (0.75) | POLBMPOKMT2ASMN1; SMN2HPGD | |
| SCHEMBL9379490 | 0.83 | KMT2A (0.69) | POLBMPOKMT2AMAPTALDH1A1 | |
| SCHEMBL8425964 | 0.82 | SMN1; SMN2 (0.79) | POLBMPOKMT2ASMN1; SMN2HPGD | |
| SCHEMBL17624909 | 0.82 | MAPT (0.83) | POLBMPOKMT2AMAPTALDH1A1 | |
| SCHEMBL12485740 | 0.81 | MPO (0.81) | POLBMPOKMT2ASMN1; SMN2MAPT | |
| SCHEMBL14304382 | 0.81 | KMT2A (0.79) | POLBMPOKMT2ASMN1; SMN2HPGD | |
| SCHEMBL8251328 | 0.80 | KMT2A (0.77) | POLBMPOKMT2ASMN1; SMN2HPGD | |
| SCHEMBL3515244 | 0.80 | KMT2A (1.00) | POLBKMT2ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL29770390 | 0.80 | KMT2A (1.00) | POLBKMT2ASMN1; SMN2HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329363-A | Substituted mercapto acid amides and their use | MERCK & CO., INC. (US) | 1982-05-11 | — | — | US | disclosed |
| US-4216160-A | IMMUNOREGULANTS FOR CORRECTING AN INBALANCE OF IMMUNE HOMEOSTASIS | MERCK & CO., INC. (US) | 1980-08-05 | — | — | US | disclosed |