Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | CASP1 | P29466 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.55 |
| ▸ | FEN1 | P39748 | 1/20 | 0.55 |
| ▸ | FLT1 | P17948 | 4/20 | 0.50 |
| ▸ | FLT4 | P35916 | 4/20 | 0.50 |
| ▸ | KDR | P35968 | 4/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Silver SCHEMBL1151256 | 0.96 | TSHR (0.63) | TSHRCASP1SMN1; SMN2ALDH1A1MAPK1 | |
| Potassium Ion SCHEMBL1303475 | 0.96 | TSHR (0.63) | TSHRCASP1SMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL29653755 | 0.96 | TSHR (0.63) | TSHRCASP1SMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL6231168 | 0.96 | TSHR (0.63) | TSHRCASP1SMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL11265039 | 0.83 | ALDH1A1 (0.63) | TSHRCASP1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL4446245 | 0.80 | CA1 (0.52) | TSHRCASP1SMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL28510712 | 0.80 | ALDH1A1 (0.48) | TSHRCASP1SMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL30185351 | 0.79 | SMN1; SMN2 (0.71) | TSHRCASP1SMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL8065539 | 0.79 | SMN1; SMN2 (0.71) | TSHRCASP1SMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL195020 | 0.79 | SMN1; SMN2 (0.71) | TSHRCASP1SMN1; SMN2ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4313850-A | METAL BIS(HALOCARBOXYLATE), OXYGENATED ORGANOTITANIUM, VANDIUM OR ZIRCONIUM COMPOUND AND AN ORGANOALUMIUM COMPOUND | STANDARD OIL COMPANY (INDIANA) (US) | 1982-02-02 | — | — | US | disclosed |