Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 known ✓ | P00915 | 3/20 | 0.52 |
| ▸ | CA2 known ✓ | P00918 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | ERCC5 | P28715 | 2/20 | 0.43 |
| ▸ | FEN1 | P39748 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8822154 | 0.98 | CA1 (0.50) | CA1CA2ALDH1A1TP53TSHR | |
| SCHEMBL28510712 | 0.95 | ALDH1A1 (0.48) | CA1CA2ALDH1A1TP53TSHR | |
| SCHEMBL29637849 | 0.90 | TSHR (0.59) | CA1CA2ALDH1A1TP53TSHR | |
| SCHEMBL653747 | 0.90 | TSHR (0.59) | CA1CA2ALDH1A1TP53TSHR | |
| SCHEMBL8822155 | 0.90 | TSHR (0.59) | CA1CA2ALDH1A1TP53TSHR | |
| SCHEMBL6231168 | 0.84 | TSHR (0.63) | CA1CA2ALDH1A1TP53TSHR | |
| SCHEMBL29653755 | 0.84 | TSHR (0.63) | CA1CA2ALDH1A1TP53TSHR | |
| SCHEMBL28343765 | 0.84 | ALDH1A1 (0.63) | CA1CA2ALDH1A1TP53TSHR | |
| 5-Chlorosalicylic Acid SCHEMBL429285 | 0.83 | CA1 (0.64) | CA1CA2ALDH1A1TP53SMN1; SMN2 | |
| Silver SCHEMBL1151256 | 0.80 | TSHR (0.63) | CA1CA2ALDH1A1TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118649643-B | Continuous chlorination reaction device and method for sodium 4-chlorophthalite | 河北彩客新材料科技股份有限公司 | 2024-11-29 | — | — | CN | claimed |
| CN-118649643-A | Continuous chlorination reaction device and method for sodium 4-chlorophthalite | 河北彩客新材料科技股份有限公司 | 2024-09-17 | — | — | CN | claimed |
| CN-118702656-B | Environment-friendly polyimide monomer preparation process | 安徽秀朗新材料科技有限公司 | 2025-06-17 | — | — | CN | disclosed |
| CN-118702656-A | Environment-friendly polyimide monomer preparation process | 安徽秀朗新材料科技有限公司 | 2024-09-27 | — | — | CN | disclosed |
| CN-117003634-A | Method for removing impurities in reaction liquid in production of biphenyl tetracarboxylic acid | 河北东丽新材料有限公司 | 2023-11-07 | — | — | CN | disclosed |
| CN-113717136-B | Synthesis method of 3,3', 4' -biphenyl tetracarboxylic dianhydride | 江西师范大学 | 2023-05-09 | — | — | CN | disclosed |
| CN-114478234-B | Refining method of 4-chlorophthalic acid monosodium salt crude product | 河北海力恒远新材料股份有限公司 | 2023-03-31 | — | — | CN | disclosed |
| CN-114656351-B | Method for treating 4-chlorophthalic acid or monosodium salt production wastewater thereof | 河北海力香料股份有限公司 | 2022-08-26 | — | — | CN | disclosed |
| CN-114656351-A | Method for treating 4-chlorophthalic acid or monosodium salt production wastewater thereof | 河北海力香料股份有限公司 | 2022-06-24 | — | — | CN | disclosed |
| CN-114478234-A | Refining method of 4-chlorophthalic acid monosodium salt crude product | 河北海力香料股份有限公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-114084994-B | Treatment method of BPDA series acidified waste brine | 河北海力香料股份有限公司 | 2022-05-03 | — | — | CN | disclosed |
| US-5047560-A | Process for producing highly pure 3,3',4,4'-biphenyltetracarboxylic acid or dianhydride thereof | HITACHI, LTD. (JP) | 1991-09-10 | — | — | US | disclosed |
| EP-0421046-A1 | Process for producing highly pure 3,3',4,4' - biphenyltetra- carboxylic acid or dianhydride thereof | HITACHI, LTD. (JP) | 1991-04-10 | — | — | EP | disclosed |
| EP-0409172-A2 | Process for dimerizing aromatic halogen compounds | MITSUBISHI KASEI CORPORATION (JP) | 1991-01-23 | — | — | EP | disclosed |
| US-4900843-A | Method for dimerization of aromatic halide compounds | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1990-02-13 | — | — | US | disclosed |
| EP-0318634-A1 | Process for dimerization of aromatic halide compounds | MITSUBISHI KASEI CORPORATION (JP) | 1989-06-07 | — | — | EP | disclosed |
| US-4727185-A | Process for preparation of 3,3',4,4'-biphenyltetracarboxylic acid salts | HITACHI, LTD. (JP) | 1988-02-23 | — | — | US | disclosed |
| US-4595470-A | Process for the preparation of benzene polycarboxylic acids | SUGITA NOBUYUKI (JP) | 1986-06-17 | — | — | US | disclosed |
| US-3965125-A | Synthesis of certain bis(phthalic anhydrides) | TRW INC. (US) | 1976-06-22 | — | — | US | disclosed |
| US-3965125-A | Synthesis of certain bis(phthalic anhydrides) | TRW INC. (US) | 1976-06-22 | — | — | US | disclosed |