Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | ACP1 | P24666 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11264138 | 0.82 | RAB9A (0.48) | ALDH1A1KMT2ANPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11255071 | 0.81 | RAB9A (0.47) | ALDH1A1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11259222 | 0.77 | NPC1 (0.49) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL11264975 | 0.76 | ALDH1A1 (0.44) | ALDH1A1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11271207 | 0.76 | MAPT (0.44) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL11262236 | 0.76 | MAPT (0.47) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL11262352 | 0.76 | MAPT (0.49) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL11269297 | 0.74 | SMN1; SMN2 (0.47) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL11269414 | 0.72 | KMT2A (0.50) | ALDH1A1KMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL11270922 | 0.71 | ALDH1A1 (0.37) | ALDH1A1KMT2AMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344946-A | ANTIARTHRITICS, ANTIRHEUMATICS | BOEHRINGER INGELHEIM GMBH (DE) | 1982-08-17 | — | — | US | disclosed |