SCHEMBL11269481

SCHEMBL11269481

C[CH]C(=O)OC(O)CCC

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 1/20 0.34
AKR1A1 P14550 1/20 0.34
CHRM3 P20309 1/20 0.34
HTR2A P28223 1/20 0.34
HTR2C P28335 1/20 0.34
ADRA1A P35348 1/20 0.34
HRH1 P35367 1/20 0.34
DRD3 P35462 1/20 0.34
SLC6A3 Q01959 1/20 0.34
HDAC1 Q13547 1/20 0.34
HDAC2 Q92769 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
TSHR P16473 3/20 0.33
CYP3A4 P08684 2/20 0.33
NFKB1 P19838 2/20 0.33
NPSR1 Q6W5P4 2/20 0.33
CTSK P43235 1/20 0.32
HDAC7 Q8WUI4 1/20 0.31
HDAC8 Q9BY41 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8676089 0.84 HCAR2 (0.40) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL8676086 0.84 HCAR2 (0.40) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL4613185 0.83 HCAR2 (0.32) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL4613181 0.83 HCAR2 (0.32) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL26503 0.81 TSHR (0.44) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL30479093 0.79 PRKCA (0.36) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL27143080 0.79 TSHR (0.42) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL9398163 0.79 ACHE (0.34)
SCHEMBL9398153 0.79 ACHE (0.34)
SCHEMBL7002370 0.78 FAAH (0.36) CHRM1AKR1A1CHRM3HTR2AHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0045354-A1 A method of dyeing and printing hydrophobic fibrous materials, and azo dyestuffs suitable therefor CASSELLA Aktiengesellschaft (DE) 1982-02-10 EP disclosed