Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11276627 | 0.99 | ABCB11 (0.45) | MAPTABCB11LMNAMAPK1HPGD | |
| SCHEMBL11261344 | 0.86 | TSHR (0.46) | MAPTABCB11LMNAMAPK1HPGD | |
| SCHEMBL11298634 | 0.82 | LMNA (0.58) | MAPTABCB11LMNAMAPK1HPGD | |
| SCHEMBL11205196 | 0.81 | HPGD (0.36) | HPGDKDM4EALDH1A1NPSR1HDAC6 | |
| SCHEMBL11292357 | 0.81 | LMNA (0.60) | MAPTABCB11LMNAMAPK1HPGD | |
| SCHEMBL11265124 | 0.81 | ABCB11 (0.44) | MAPTABCB11LMNAMAPK1ALDH1A1 | |
| SCHEMBL11269045 | 0.81 | MAPT (0.57) | MAPTABCB11LMNAMAPK1KDM4E | |
| SCHEMBL11204241 | 0.81 | HPGD (0.35) | HPGDKDM4EALDH1A1NPSR1HDAC6 | |
| SCHEMBL11272940 | 0.80 | LMNA (0.58) | MAPTABCB11LMNAMAPK1KDM4E | |
| SCHEMBL11140301 | 0.79 | TMEM97 (0.39) | MAPTABCB11LMNAMAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4324796-A | HYPOGLYCEMIC AGENTS, HYPOKETONEMIC AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1982-04-13 | — | — | US | disclosed |