Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.36 |
| ▸ | RAD51 | Q06609 | 3/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11279186 | 0.89 | SMN1; SMN2 (0.42) | SMN1; SMN2CYP11B2XDHNOTUMRAD51 | |
| SCHEMBL11266662 | 0.84 | PTGS2 (0.42) | SMN1; SMN2RAD51MAPTKMT2A | |
| SCHEMBL11267429 | 0.84 | MAPT (0.41) | SMN1; SMN2CYP11B2XDHGAALMNA | |
| SCHEMBL11263206 | 0.83 | HCAR1 (0.42) | CYP11B2XDHNOTUMADRB1GAA | |
| SCHEMBL11267538 | 0.82 | CYP11B2 (0.32) | CYP11B2NOTUM | |
| SCHEMBL11269982 | 0.82 | POLB (0.39) | CYP11B2LMNAMAPT | |
| SCHEMBL11270269 | 0.79 | SMN1; SMN2 (0.39) | SMN1; SMN2GAALMNAMAPTKMT2A | |
| SCHEMBL11270609 | 0.79 | HCAR1 (0.36) | CYP11B2MAPT | |
| SCHEMBL11274262 | 0.79 | HCAR1 (0.40) | — | |
| SCHEMBL11264984 | 0.79 | KMT2A (0.39) | SMN1; SMN2CYP11B2XDHGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4350701-A | 1-(Trihalomethyl-sulfenyl)-4-aryl-1,2,4-triazolin-5-ones, and process for controlling fungi | BASF AKTIENGESELLSCHAFT (DE) | 1982-09-21 | — | — | US | disclosed |