Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 5/20 | 0.57 |
| ▸ | HTR1A | P08908 | 5/20 | 0.57 |
| ▸ | HRH1 | P35367 | 3/20 | 0.57 |
| ▸ | DRD2 | P14416 | 3/20 | 0.57 |
| ▸ | HTR2A | P28223 | 3/20 | 0.57 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11284442 | 0.99 | HTR1A (0.56) | DRD3HTR1AHRH1DRD2HTR2A | |
| SCHEMBL11279327 | 0.96 | HTR1A (0.53) | DRD3HTR1AHRH1DRD2HTR2A | |
| SCHEMBL11273882 | 0.91 | DRD2 (0.55) | DRD3HTR1AHRH1DRD2HTR2A | |
| SCHEMBL11264278 | 0.90 | HTR1A (0.49) | DRD3HTR1AHRH1DRD2HTR2A | |
| SCHEMBL11290067 | 0.88 | HTR1A (0.59) | DRD3HTR1AHRH1DRD2HTR2A | |
| SCHEMBL11270171 | 0.88 | KCNH2 (0.57) | HTR1ADRD2HTR2ASIGMAR1LMNA | |
| SCHEMBL11277199 | 0.87 | SLC6A2 (0.56) | DRD3HTR1AHRH1DRD2HTR2A | |
| SCHEMBL11284128 | 0.86 | HTR7 (0.59) | DRD3DRD2HTR2ASIGMAR1 | |
| SCHEMBL11292019 | 0.86 | TSHR (0.59) | DRD3HTR1AHRH1DRD2HTR2A | |
| SCHEMBL11266553 | 0.86 | HTR1A (0.62) | DRD3HTR1AHRH1DRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-56127368-A | — | — | None | — | — | JP | disclosed |
| US-4339580-A | TRANQUILIZERS, SEDATIVES | MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) | 1982-07-13 | — | — | US | disclosed |
| EP-0021368-B1 | PIPERAZINYLALKOXYINDANES AND ACID ADDITION SALTS THEREOF | MITSUBISHI KASEI CORPORATION (JP) | 1982-05-19 | — | — | EP | disclosed |
| JP-S56127368-A | PIPERAZINYLALKOXYINDANES AND THEIR ACID ADDITION SALTS | MITSUBISHI CHEM IND LTD | 1981-10-06 | — | — | JP | disclosed |
| EP-0021368-A1 | Piperazinylalkoxyindanes and acid addition salts thereof | MITSUBISHI KASEI CORPORATION (JP) | 1981-01-07 | — | — | EP | disclosed |