SCHEMBL1127089

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1127207	0.95	GLO1 (0.39)	GLO1ALDH1A1HPGDCNR1BRD4
	SCHEMBL1126990	0.90	CNR1 (0.45)	GLO1ALDH1A1HPGDCNR1BRD4
	SCHEMBL1126944	0.85	KDM4E (0.41)	HPGDBRD4MAPK1RAB9ANPC1
	SCHEMBL1127094	0.82	TYR (0.49)	GLO1ALDH1A1HPGDCNR1BRD4
	SCHEMBL1126707	0.80	BRD4 (0.42)	ALDH1A1HPGDCNR1BRD4LMNA
	SCHEMBL1988099	0.80	BRD4 (0.37)	GLO1ALDH1A1HPGDCNR1BRD4
	SCHEMBL1126929	0.78	TYR (0.46)	ALDH1A1BRD4CNR2ADORA2B
	SCHEMBL1127015	0.78	RAB9A (0.49)	ALDH1A1MAPK1RAB9ANPC1
	SCHEMBL1126844	0.78	KDM4E (0.46)	ALDH1A1CNR1BRD4MAPK1RAB9A
	SCHEMBL1127357	0.77	BRD4 (0.37)	ALDH1A1CNR1BRD4RAB9ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.