SCHEMBL1126944

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1126844	0.91	KDM4E (0.46)	KDM4ERAB9ANPC1USP2TP53
	SCHEMBL1127089	0.85	GLO1 (0.42)	RAB9ANPC1MAPK1BRD4HPGD
	SCHEMBL1127094	0.83	TYR (0.49)	KDM4ERAB9ANPC1BRD4HPGD
	SCHEMBL1127276	0.81	BRD4 (0.40)	KDM4ERAB9ANPC1SMN1; SMN2BRD4
	SCHEMBL1127207	0.81	GLO1 (0.39)	TP53MAPK1BRD4MAPTHPGD
	SCHEMBL1127040	0.81	ALDH1A1 (0.38)	KDM4ERAB9ANPC1TP53SMN1; SMN2
	SCHEMBL1126608	0.79	ALDH1A1 (0.39)	RAB9AUSP2MAPK1BRD4CYP3A4
	SCHEMBL1126929	0.79	TYR (0.46)	KDM4EBRD4TLR8TYR
	SCHEMBL1126990	0.78	CNR1 (0.45)	KDM4ESMN1; SMN2BRD4HPGD
	SCHEMBL1127469	0.76	BRD4 (0.38)	KDM4ERAB9ASMN1; SMN2MAPK1BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.